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Our Product

Renovate harnesses the natural mechanisms of the kidney as a therapeutic approach.

 

Our lead product, KOSEC01, is a combination of anti-fibrotic and pro-regenerative biomolecules produced by human kidney cells grown in a unique 3D culture.

 

This is the first secretome-based drug for CKD, designed to treat all patients and prevent end-stage renal failure.

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The Advantages of KOSEC01

A Breakthrough Treatment for CKD

Most patients with end-stage renal disease (ESRD) ultimately require dialysis or a kidney transplant. KOSEC01 has the potential to improve kidney function, enhance quality of life, and  prevent disease progression.

A Universal Solution

Unlike existing treatments, KOSEC01 has a unique anti-fibrotic and regenerative effect on the kidneys, making it effective for all CKD patients, regardless of the underlying cause. No other drug on the market offers this level of versatility.

Cell-Free
Therapy

KOSEC01 is a secretome-based drug derived from a proprietary 3D culture of kidney OrganoSpheroids. As an off-the-shelf treatment, it eliminates the need for personalized medicine, making it accessible to all patients.

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Address

Sheba Medical Center, Derech Sheba, Ramat Gan, Israel

Email

Linkedin

Phone

+972-3-5307600

Contact Us

© 2025 by RenoVate Therapeutics

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